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The PDE5 enzyme breaks down a substance that is responsible for blood flow in the penis.

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Read about natural remedies for erectile dysfunction (ED or impotence), including exercise, acupuncture, arginine, DHEA, ginseng, pomegranate juice, yohimbe, horny goat weed, and ginkgo biloba. and one of the original clinical investigators for the ED drug Viagra (whether herbal remedies or not). Where to buy herbal viagra online. Cheap prices and no prescription required. Find causes of erectile dysfunction (ED), or impotence. Sep 26,  · One way drugs like Viagra work is to inhibit an enzyme called PDE-5, thereby keeping blood flowing to the penis. WebMD does not provide medical advice, diagnosis or treatment.