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Archived from the original on 26 September Archived from the original on 22 October The Globe and Mail.

Retrieved 25 October Sildenafil should not be used if sexual activity is inadvisable due to underlying cardiovascular risk factors [19]. From Wikipedia, the free encyclopedia. In , the Medicines and Healthcare products Regulatory Agency enacted legislation that expanded this nationwide.

The substance is the same under both trade names.

In July , the FDA found that sildenafil could lead to vision impairment in rare cases [14] and a number of studies have linked sildenafil use with non-arteritic anterior ischemic optic neuropathy.

Pfizer scientists Andrew Bell, David Brown, and Nicholas Terrett originally discovered sildenafil as a treatment for various cardiovascular disorders. Common side effects include headaches and heartburn , as well as flushed skin.

This patent was published in and will expire in Retrieved 2 April Retrieved August 10, Drugs for erectile dysfunction and premature ejaculation.


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    Sildenafil is sale down in the liver by hepatic metabolism using cytochrome p enzymes, pill CYP 3A4 major viagrasale also by CYP2C9 minor route hepatic isoenzymes. InPfizer pill a patent covering the substance sildenafil viagra its use to treat cardiovascular diseases.